EVORAO

Class: Nucleic acid (NucleicAcid)

Nucleic acid related to a pathogen. It can be extracted or synthetic.

URI: EVORAO:NucleicAcid

 classDiagram
    class NucleicAcid
    click NucleicAcid href "../NucleicAcid"
      Product <|-- NucleicAcid
        click Product href "../Product"
      
      NucleicAcid : accessPointUrl
        
      NucleicAcid : additionalCategory
        
          
    
    
    NucleicAcid --> "* _recommended_" ProductCategory : additionalCategory
    click ProductCategory href "../ProductCategory"

        
      NucleicAcid : availability
        
      NucleicAcid : biologicalMaterialOrigin
        
          
    
    
    NucleicAcid --> "1" BiologicalMaterialOrigin : biologicalMaterialOrigin
    click BiologicalMaterialOrigin href "../BiologicalMaterialOrigin"

        
      NucleicAcid : biosafetyLevel
        
          
    
    
    NucleicAcid --> "0..1" BiosafetyLevel : biosafetyLevel
    click BiosafetyLevel href "../BiosafetyLevel"

        
      NucleicAcid : biosafetyRestrictions
        
      NucleicAcid : canBeUsedToProduceGmo
        
      NucleicAcid : category
        
          
    
    
    NucleicAcid --> "1" ProductCategory : category
    click ProductCategory href "../ProductCategory"

        
      NucleicAcid : certification
        
          
    
    
    NucleicAcid --> "*" Certification : certification
    click Certification href "../Certification"

        
      NucleicAcid : clonedIntoPlasmid
        
          
    
    
    NucleicAcid --> "0..1 _recommended_" ExpressionVector : clonedIntoPlasmid
    click ExpressionVector href "../ExpressionVector"

        
      NucleicAcid : clonedNucleicAcid
        
      NucleicAcid : collection
        
          
    
    
    NucleicAcid --> "1..*" Collection : collection
    click Collection href "../Collection"

        
      NucleicAcid : complementaryDocument
        
          
    
    
    NucleicAcid --> "*" Document : complementaryDocument
    click Document href "../Document"

        
      NucleicAcid : contactPoint
        
          
    
    
    NucleicAcid --> "0..1 _recommended_" ContactPoint : contactPoint
    click ContactPoint href "../ContactPoint"

        
      NucleicAcid : dateIssued
        
      NucleicAcid : dateModified
        
      NucleicAcid : description
        
      NucleicAcid : doi
        
          
    
    
    NucleicAcid --> "*" Doi : doi
    click Doi href "../Doi"

        
      NucleicAcid : externalRelatedReference
        
          
    
    
    NucleicAcid --> "*" ExternalRelatedReference : externalRelatedReference
    click ExternalRelatedReference href "../ExternalRelatedReference"

        
      NucleicAcid : fundingSource
        
          
    
    
    NucleicAcid --> "*" FundingSource : fundingSource
    click FundingSource href "../FundingSource"

        
      NucleicAcid : genBankFileOfTheConstruct
        
          
    
    
    NucleicAcid --> "*" Data : genBankFileOfTheConstruct
    click Data href "../Data"

        
      NucleicAcid : iataClassification
        
          
    
    
    NucleicAcid --> "1" IataClassification : iataClassification
    click IataClassification href "../IataClassification"

        
      NucleicAcid : identificationTechnique
        
      NucleicAcid : identifier
        
      NucleicAcid : internalReference
        
      NucleicAcid : iri
        
      NucleicAcid : keyword
        
      NucleicAcid : keywords
        
          
    
    
    NucleicAcid --> "1..*" Keyword : keywords
    click Keyword href "../Keyword"

        
      NucleicAcid : materialSafetyDataSheet
        
          
    
    
    NucleicAcid --> "0..1" MaterialSafetyDataSheet : materialSafetyDataSheet
    click MaterialSafetyDataSheet href "../MaterialSafetyDataSheet"

        
      NucleicAcid : mutationObserved
        
      NucleicAcid : note
        
      NucleicAcid : observedMutations
        
      NucleicAcid : originator
        
          
    
    
    NucleicAcid --> "0..1" Originator : originator
    click Originator href "../Originator"

        
      NucleicAcid : pathogenIdentification
        
          
    
    
    NucleicAcid --> "1..*" PathogenIdentification : pathogenIdentification
    click PathogenIdentification href "../PathogenIdentification"

        
      NucleicAcid : plasmidSelection
        
          
    
    
    NucleicAcid --> "* _recommended_" PlasmidSelection : plasmidSelection
    click PlasmidSelection href "../PlasmidSelection"

        
      NucleicAcid : preparationTechnique
        
      NucleicAcid : productPicture
        
          
    
    
    NucleicAcid --> "*" Image : productPicture
    click Image href "../Image"

        
      NucleicAcid : provider
        
          
    
    
    NucleicAcid --> "1" Provider : provider
    click Provider href "../Provider"

        
      NucleicAcid : publisher
        
          
    
    
    NucleicAcid --> "0..1" PersonOrOrganization : publisher
    click PersonOrOrganization href "../PersonOrOrganization"

        
      NucleicAcid : qualityGrading
        
      NucleicAcid : refSku
        
      NucleicAcid : regionEncompassedInThisProduct
        
      NucleicAcid : riskGroup
        
          
    
    
    NucleicAcid --> "0..1 _recommended_" RiskGroup : riskGroup
    click RiskGroup href "../RiskGroup"

        
      NucleicAcid : sequence
        
          
    
    
    NucleicAcid --> "* _recommended_" Sequence : sequence
    click Sequence href "../Sequence"

        
      NucleicAcid : sequenceChecked
        
      NucleicAcid : sequencing
        
      NucleicAcid : shippingConditions
        
      NucleicAcid : storageConditions
        
      NucleicAcid : tagSequence
        
          
    
    
    NucleicAcid --> "0..1 _recommended_" TagSequence : tagSequence
    click TagSequence href "../TagSequence"

        
      NucleicAcid : technicalRecommendation
        
      NucleicAcid : thirdPartyDistributionConsent
        
      NucleicAcid : titer
        
      NucleicAcid : title
        
      NucleicAcid : unitCost
        
      NucleicAcid : unitCostCurrency
        
      NucleicAcid : unitCostNote
        
      NucleicAcid : unitDefinition
        
      NucleicAcid : usageRestrictions
        
      NucleicAcid : version
        
      

Inheritance

Slots

Name Cardinality and Range Description Inheritance
biologicalMaterialOrigin 1
BiologicalMaterialOrigin
Information about the origin of the biological material, essential for access… direct
genBankFileOfTheConstruct *
Data
A GenBank formatted file that contains detailed sequence and annotation infor… direct
sequence * recommended
Sequence
The related sequence information from a sequence provider or in fasta format direct
clonedNucleicAcid 1
Boolean
Specification of the terms and parameters for transporting direct
clonedIntoPlasmid 0..1 recommended
ExpressionVector
The plasmid into which the nucleic acid has been cloned direct
plasmidSelection * recommended
PlasmidSelection
Specific selectable markers in the plasmid, such as antibiotic resistance gen… direct
tagSequence 0..1 recommended
TagSequence
The name of the DNA coding sequence or corresponding peptide/protein sequence… direct
regionEncompassedInThisProduct 0..1 recommended
String
The specific region encompassed in the product direct
mutationObserved 0..1 recommended
Boolean
Indicates if the current nucleic acid has No mutation compared to the referen… direct
observedMutations 0..1
String
The specific mutations that have been identified and documented in the nuclei… direct
identificationTechnique 0..1
String
A method or procedure used to detect, identify, and confirm the presence of a… direct
sequencing 1
String
Refers to the level of sequencing performed on the nucleic acid direct
titer 0..1
String
The titer value, its corresponding unit, and the method of quantification (e direct
sequenceChecked 0..1 recommended
Boolean
Tell whether or not the sequence of the product was controlled, which is expe… direct
iataClassification 1
IataClassification
The corresponding International Air Transport Association (IATA)’s category f… Product
shippingConditions 1
String
Specification of the terms and parameters for transporting Product
materialSafetyDataSheet 0..1
MaterialSafetyDataSheet
A Material Safety Data Sheet (MSDS) or Safety Data Sheet (SDS) is a standardi… Product
originator 0..1
Originator
The individual or organization responsible for the original discovery, isolat… Product
storageConditions 1
String
Specifies the conditions under which the product has to be stored to maintain… Product
thirdPartyDistributionConsent 0..1
Boolean
Indicates whether the biological material can be distributed without restrict… Product
usageRestrictions 0..1
String
Specifies any limitations or conditions on the use of the biological material… Product
preparationTechnique 0..1
String
The technique, method, or procedure employed to obtain or prepare the materia… Product
accessPointUrl 1
Uri
The URL that permits to access to the product/service detailed description pa… ProductOrService
refSku 1
String
The reference or the stock keeping unit of the service or item provided in th… ProductOrService
unitDefinition 0..1 recommended
String
A short description of what is delivered when one unit of this item is ordere… ProductOrService
category 1
ProductCategory
The main category of the service or product ProductOrService
additionalCategory * recommended
ProductCategory
Any category apart from its main category in which this product or service ca… ProductOrService
unitCost 0..1 recommended
Decimal
The cost per access for one unit as defined by the unit definition ProductOrService
unitCostCurrency 0..1 recommended
String
The currency in which the unit cost is expressed, following ISO 4217 three-le… ProductOrService
unitCostNote 0..1
String
A free-text note describing special conditions or cases where the cost cannot… ProductOrService
qualityGrading 0..1
String
Information that permits to assess the quality level of what will be provided ProductOrService
pathogenIdentification 1..*
PathogenIdentification
The identification of the pathogen or group of pathogens (e ProductOrService
doi *
Doi
A Digital Object Identifier (DOI) that can be related ProductOrService
riskGroup 0..1 recommended
RiskGroup
The highest risk group related to this resource ProductOrService
biosafetyLevel 0..1
BiosafetyLevel
The level of biocontainment required or applied in the facility where the bio… ProductOrService
biosafetyRestrictions 0..1
String
Information about guidelines and regulations designed to prevent the exposure… ProductOrService
canBeUsedToProduceGmo 0..1 recommended
Boolean
Indicates if the current service or product can be used to produce GMO ProductOrService
provider 1
Provider
A provider of this product or service, as a specific organization ProductOrService
collection 1..*
Collection
The collection(s) to which belongs this item ProductOrService
keywords 1..*
Keyword
List of terms used to tag and categorize this Item ProductOrService
availability 1
String
The state or condition in which this item is accessible and ready for use or … ProductOrService
complementaryDocument *
Document
Any additional documents that provide supplementary information, instructions… ProductOrService
technicalRecommendation 0..1
String
Expert advice or guidelines provided to ensure the optimal use, performance, … ProductOrService
productPicture *
Image
A picture that can represent the item ProductOrService
externalRelatedReference *
ExternalRelatedReference
A reference that permits to retrieve another related item from an external pr… ProductOrService
certification *
Certification
Any certification related to the current product or service; e ProductOrService
internalReference 0..1
String
Any reference or indication to be used for local retrieval purpose ProductOrService
note 0..1
String
An aditional information as a textual comment ProductOrService
contactPoint 0..1 recommended
ContactPoint
An information that allows someone to establish communication ProductOrService
fundingSource *
FundingSource
A program, grant, or project providing financial support for the access or us… ProductOrService
title 1
String
A name given to the resource Dataset
description 1 recommended
String
A short explanation of the characteristics, features, or nature of the curren… Dataset
version 0..1 recommended
String
The version indicator (name or identifier) of a resource Dataset
keyword *
String
A keyword or tag describing the resource Resource
dateIssued 0..1
Datetime
Date of formal issuance (e Resource
dateModified 0..1
Datetime
Most recent date on which the resource was changed, updated or modified Resource
identifier *
String
A unique identifier of the resource being described or cataloged Resource
iri *
Uri
International Resource Identifier (IRI) that uniquely identifies or refers to… Resource
publisher 0..1
PersonOrOrganization
The entity responsible for making the resource available Resource

Identifier and Mapping Information

Schema Source

Mappings

Mapping Type Mapped Value
self EVORAO:NucleicAcid
native EVORAO:NucleicAcid
related mi:0318, mi:0318
close wd:Q123619, ncit:C706, snomed:27380003, sio:010008, chebi:33696, wd:Q123619, ncit:C706, snomed:27380003, sio:010008, chebi:33696

LinkML Source

Direct

```yaml name: NucleicAcid description: Nucleic acid related to a pathogen. It can be extracted or synthetic. title: Nucleic acid from_schema: https://w3id.org/evorao/ close_mappings: - wd:Q123619 - ncit:C706 - snomed:27380003 - sio:010008 - chebi:33696 - wd:Q123619 - ncit:C706 - snomed:27380003 - sio:010008 - chebi:33696 related_mappings: - mi:0318 - mi:0318 is_a: Product slots: - biologicalMaterialOrigin - genBankFileOfTheConstruct - sequence - clonedNucleicAcid - clonedIntoPlasmid - plasmidSelection - tagSequence - regionEncompassedInThisProduct - mutationObserved - observedMutations - identificationTechnique - sequencing - titer - sequenceChecked slot_usage: biologicalMaterialOrigin: name: biologicalMaterialOrigin description: Information about the origin of the biological material, essential for access, utilization, and benefit-sharing of genetic resources in compliance with the Nagoya Protocol. title: biological material origin related_mappings: - sepio:0000058 domain_of: - NucleicAcid - Protein - Pathogen range: BiologicalMaterialOrigin required: true multivalued: false genBankFileOfTheConstruct: name: genBankFileOfTheConstruct description: A GenBank formatted file that contains detailed sequence and annotation information of a nucleic acid construct. title: GenBank file of the construct domain_of: - NucleicAcid range: Data required: false multivalued: true sequence: name: sequence description: The related sequence information from a sequence provider or in fasta format. title: sequence comments: - Sequence information is logically one of the minimal quality requirements for entities such as pathogens, nucleic acids, and proteins, and should always be provided. However, in some rare cases, a nucleic acid may still be valuable even if it has not been sequenced after being extracted from identified material. In such exceptional cases, the sequence may legitimately be missing. close_mappings: - geno:0000239 - bao:0002817 related_mappings: - uniprotrdfs:sequence domain_of: - NucleicAcid - RecombinantPartIdentification - Protein - Pathogen range: Sequence required: false recommended: true multivalued: true clonedNucleicAcid: name: clonedNucleicAcid description: Specification of the terms and parameters for transporting. title: cloned nucleic acid domain_of: - NucleicAcid range: boolean required: true multivalued: false clonedIntoPlasmid: name: clonedIntoPlasmid description: The plasmid into which the nucleic acid has been cloned. title: cloned into plasmid domain_of: - NucleicAcid range: ExpressionVector required: false recommended: true multivalued: false plasmidSelection: name: plasmidSelection description: Specific selectable markers in the plasmid, such as antibiotic resistance genes, used to identify and maintain cells that contain the plasmid. title: plasmid selection domain_of: - NucleicAcid range: PlasmidSelection required: false recommended: true multivalued: true tagSequence: name: tagSequence description: The name of the DNA coding sequence or corresponding peptide/protein sequence fused to a sequence of interest, used to facilitate experimental operations such as purification, detection, localization, tracking, solubility enhancement, or selection. Applicable to both proteins and nucleic acids. title: tag sequence comments: - The tagSequence is strongly recommended for cloned nucleic acids and proteins but may be absent in certain cases, such as for some non-cloned nucleic acids. exact_mappings: - bao:0002796 domain_of: - NucleicAcid - Protein range: TagSequence required: false recommended: true multivalued: false regionEncompassedInThisProduct: name: regionEncompassedInThisProduct description: The specific region encompassed in the product. title: region encompassed in this Product comments: - The regionEncompassedInThisProduct property is strongly recommended for cloned nucleic acids, as it provides essential information that greatly improves the clarity and precision of the description for the user. domain_of: - NucleicAcid range: string required: false recommended: true multivalued: false mutationObserved: name: mutationObserved description: Indicates if the current nucleic acid has No mutation compared to the reference sequence if the value is set to false or if it contains mutations (no frameshift, no unexpected STOP codon) if set to true. title: mutation observed comments: - Except for non-sequenced nucleic acids, for which mutations cannot be assessed, it is strongly recommended to determine whether any mutations are present in the provided sequenced nucleic acid. domain_of: - NucleicAcid range: boolean required: false recommended: true multivalued: false observedMutations: name: observedMutations description: The specific mutations that have been identified and documented in the nucleic acid sequence. title: observed mutations domain_of: - NucleicAcid range: string required: false multivalued: false identificationTechnique: name: identificationTechnique description: A method or procedure used to detect, identify, and confirm the presence of a specific nucleic acid sequence, pathogen, or associated constructs. This may involve various techniques such as PCR, sequencing, hybridization, or other molecular methods, utilizing specific tools and procedures for accurate detection and analysis. title: identification technique domain_of: - NucleicAcid - Pathogen range: string required: false multivalued: false sequencing: name: sequencing description: Refers to the level of sequencing performed on the nucleic acid. Possible values include 'Not sequenced' (no sequencing has been performed), 'Partly sequenced' (only a portion of the nucleic acid sequence has been determined), and 'Fully sequenced' (the entire nucleic acid sequence has been determined). title: sequencing comments: - Cloned products have to be sequenced. domain_of: - NucleicAcid range: string required: true multivalued: false titer: name: titer description: The titer value, its corresponding unit, and the method of quantification (e.g., RT-qPCR, TCID50), representing the concentration or amount of unit present in the sample. The titer corresponds to the highest dilution factor that still yields a positive reading. title: titer domain_of: - NucleicAcid - Pathogen range: string required: false multivalued: false sequenceChecked: name: sequenceChecked description: Tell whether or not the sequence of the product was controlled, which is expected for sequenced nucleic acids and especially important for cloned ones. title: sequence checked comments: - For non-sequenced nucleic acids, the sequenceChecked value cannot be assessed. In all other cases, it is strongly recommended to indicate whether the sequence verification has been performed or not. For cloned products in particular, providing this information is especially meaningful, as sequence verification is a key element in confirming the integrity of the cloned construct and is therefore expected to be documented whenever available. related_mappings: - iceo:0000336 domain_of: - NucleicAcid range: boolean required: false recommended: true multivalued: false ```

Induced

```yaml name: NucleicAcid description: Nucleic acid related to a pathogen. It can be extracted or synthetic. title: Nucleic acid from_schema: https://w3id.org/evorao/ close_mappings: - wd:Q123619 - ncit:C706 - snomed:27380003 - sio:010008 - chebi:33696 - wd:Q123619 - ncit:C706 - snomed:27380003 - sio:010008 - chebi:33696 related_mappings: - mi:0318 - mi:0318 is_a: Product slot_usage: biologicalMaterialOrigin: name: biologicalMaterialOrigin description: Information about the origin of the biological material, essential for access, utilization, and benefit-sharing of genetic resources in compliance with the Nagoya Protocol. title: biological material origin related_mappings: - sepio:0000058 domain_of: - NucleicAcid - Protein - Pathogen range: BiologicalMaterialOrigin required: true multivalued: false genBankFileOfTheConstruct: name: genBankFileOfTheConstruct description: A GenBank formatted file that contains detailed sequence and annotation information of a nucleic acid construct. title: GenBank file of the construct domain_of: - NucleicAcid range: Data required: false multivalued: true sequence: name: sequence description: The related sequence information from a sequence provider or in fasta format. title: sequence comments: - Sequence information is logically one of the minimal quality requirements for entities such as pathogens, nucleic acids, and proteins, and should always be provided. However, in some rare cases, a nucleic acid may still be valuable even if it has not been sequenced after being extracted from identified material. In such exceptional cases, the sequence may legitimately be missing. close_mappings: - geno:0000239 - bao:0002817 related_mappings: - uniprotrdfs:sequence domain_of: - NucleicAcid - RecombinantPartIdentification - Protein - Pathogen range: Sequence required: false recommended: true multivalued: true clonedNucleicAcid: name: clonedNucleicAcid description: Specification of the terms and parameters for transporting. title: cloned nucleic acid domain_of: - NucleicAcid range: boolean required: true multivalued: false clonedIntoPlasmid: name: clonedIntoPlasmid description: The plasmid into which the nucleic acid has been cloned. title: cloned into plasmid domain_of: - NucleicAcid range: ExpressionVector required: false recommended: true multivalued: false plasmidSelection: name: plasmidSelection description: Specific selectable markers in the plasmid, such as antibiotic resistance genes, used to identify and maintain cells that contain the plasmid. title: plasmid selection domain_of: - NucleicAcid range: PlasmidSelection required: false recommended: true multivalued: true tagSequence: name: tagSequence description: The name of the DNA coding sequence or corresponding peptide/protein sequence fused to a sequence of interest, used to facilitate experimental operations such as purification, detection, localization, tracking, solubility enhancement, or selection. Applicable to both proteins and nucleic acids. title: tag sequence comments: - The tagSequence is strongly recommended for cloned nucleic acids and proteins but may be absent in certain cases, such as for some non-cloned nucleic acids. exact_mappings: - bao:0002796 domain_of: - NucleicAcid - Protein range: TagSequence required: false recommended: true multivalued: false regionEncompassedInThisProduct: name: regionEncompassedInThisProduct description: The specific region encompassed in the product. title: region encompassed in this Product comments: - The regionEncompassedInThisProduct property is strongly recommended for cloned nucleic acids, as it provides essential information that greatly improves the clarity and precision of the description for the user. domain_of: - NucleicAcid range: string required: false recommended: true multivalued: false mutationObserved: name: mutationObserved description: Indicates if the current nucleic acid has No mutation compared to the reference sequence if the value is set to false or if it contains mutations (no frameshift, no unexpected STOP codon) if set to true. title: mutation observed comments: - Except for non-sequenced nucleic acids, for which mutations cannot be assessed, it is strongly recommended to determine whether any mutations are present in the provided sequenced nucleic acid. domain_of: - NucleicAcid range: boolean required: false recommended: true multivalued: false observedMutations: name: observedMutations description: The specific mutations that have been identified and documented in the nucleic acid sequence. title: observed mutations domain_of: - NucleicAcid range: string required: false multivalued: false identificationTechnique: name: identificationTechnique description: A method or procedure used to detect, identify, and confirm the presence of a specific nucleic acid sequence, pathogen, or associated constructs. This may involve various techniques such as PCR, sequencing, hybridization, or other molecular methods, utilizing specific tools and procedures for accurate detection and analysis. title: identification technique domain_of: - NucleicAcid - Pathogen range: string required: false multivalued: false sequencing: name: sequencing description: Refers to the level of sequencing performed on the nucleic acid. Possible values include 'Not sequenced' (no sequencing has been performed), 'Partly sequenced' (only a portion of the nucleic acid sequence has been determined), and 'Fully sequenced' (the entire nucleic acid sequence has been determined). title: sequencing comments: - Cloned products have to be sequenced. domain_of: - NucleicAcid range: string required: true multivalued: false titer: name: titer description: The titer value, its corresponding unit, and the method of quantification (e.g., RT-qPCR, TCID50), representing the concentration or amount of unit present in the sample. The titer corresponds to the highest dilution factor that still yields a positive reading. title: titer domain_of: - NucleicAcid - Pathogen range: string required: false multivalued: false sequenceChecked: name: sequenceChecked description: Tell whether or not the sequence of the product was controlled, which is expected for sequenced nucleic acids and especially important for cloned ones. title: sequence checked comments: - For non-sequenced nucleic acids, the sequenceChecked value cannot be assessed. In all other cases, it is strongly recommended to indicate whether the sequence verification has been performed or not. For cloned products in particular, providing this information is especially meaningful, as sequence verification is a key element in confirming the integrity of the cloned construct and is therefore expected to be documented whenever available. related_mappings: - iceo:0000336 domain_of: - NucleicAcid range: boolean required: false recommended: true multivalued: false attributes: biologicalMaterialOrigin: name: biologicalMaterialOrigin description: Information about the origin of the biological material, essential for access, utilization, and benefit-sharing of genetic resources in compliance with the Nagoya Protocol. title: biological material origin from_schema: https://w3id.org/evorao/ related_mappings: - sepio:0000058 rank: 1000 alias: biologicalMaterialOrigin owner: NucleicAcid domain_of: - NucleicAcid - Protein - Pathogen range: BiologicalMaterialOrigin required: true multivalued: false genBankFileOfTheConstruct: name: genBankFileOfTheConstruct description: A GenBank formatted file that contains detailed sequence and annotation information of a nucleic acid construct. title: GenBank file of the construct from_schema: https://w3id.org/evorao/ rank: 1000 alias: genBankFileOfTheConstruct owner: NucleicAcid domain_of: - NucleicAcid range: Data required: false multivalued: true sequence: name: sequence description: The related sequence information from a sequence provider or in fasta format. title: sequence comments: - Sequence information is logically one of the minimal quality requirements for entities such as pathogens, nucleic acids, and proteins, and should always be provided. However, in some rare cases, a nucleic acid may still be valuable even if it has not been sequenced after being extracted from identified material. In such exceptional cases, the sequence may legitimately be missing. from_schema: https://w3id.org/evorao/ close_mappings: - geno:0000239 - bao:0002817 related_mappings: - uniprotrdfs:sequence rank: 1000 alias: sequence owner: NucleicAcid domain_of: - NucleicAcid - RecombinantPartIdentification - Protein - Pathogen range: Sequence required: false recommended: true multivalued: true clonedNucleicAcid: name: clonedNucleicAcid description: Specification of the terms and parameters for transporting. title: cloned nucleic acid from_schema: https://w3id.org/evorao/ rank: 1000 alias: clonedNucleicAcid owner: NucleicAcid domain_of: - NucleicAcid range: boolean required: true multivalued: false clonedIntoPlasmid: name: clonedIntoPlasmid description: The plasmid into which the nucleic acid has been cloned. title: cloned into plasmid from_schema: https://w3id.org/evorao/ rank: 1000 alias: clonedIntoPlasmid owner: NucleicAcid domain_of: - NucleicAcid range: ExpressionVector required: false recommended: true multivalued: false plasmidSelection: name: plasmidSelection description: Specific selectable markers in the plasmid, such as antibiotic resistance genes, used to identify and maintain cells that contain the plasmid. title: plasmid selection from_schema: https://w3id.org/evorao/ rank: 1000 alias: plasmidSelection owner: NucleicAcid domain_of: - NucleicAcid range: PlasmidSelection required: false recommended: true multivalued: true tagSequence: name: tagSequence description: The name of the DNA coding sequence or corresponding peptide/protein sequence fused to a sequence of interest, used to facilitate experimental operations such as purification, detection, localization, tracking, solubility enhancement, or selection. Applicable to both proteins and nucleic acids. title: tag sequence comments: - The tagSequence is strongly recommended for cloned nucleic acids and proteins but may be absent in certain cases, such as for some non-cloned nucleic acids. from_schema: https://w3id.org/evorao/ exact_mappings: - bao:0002796 rank: 1000 alias: tagSequence owner: NucleicAcid domain_of: - NucleicAcid - Protein range: TagSequence required: false recommended: true multivalued: false regionEncompassedInThisProduct: name: regionEncompassedInThisProduct description: The specific region encompassed in the product. title: region encompassed in this Product comments: - The regionEncompassedInThisProduct property is strongly recommended for cloned nucleic acids, as it provides essential information that greatly improves the clarity and precision of the description for the user. from_schema: https://w3id.org/evorao/ rank: 1000 alias: regionEncompassedInThisProduct owner: NucleicAcid domain_of: - NucleicAcid range: string required: false recommended: true multivalued: false mutationObserved: name: mutationObserved description: Indicates if the current nucleic acid has No mutation compared to the reference sequence if the value is set to false or if it contains mutations (no frameshift, no unexpected STOP codon) if set to true. title: mutation observed comments: - Except for non-sequenced nucleic acids, for which mutations cannot be assessed, it is strongly recommended to determine whether any mutations are present in the provided sequenced nucleic acid. from_schema: https://w3id.org/evorao/ rank: 1000 alias: mutationObserved owner: NucleicAcid domain_of: - NucleicAcid range: boolean required: false recommended: true multivalued: false observedMutations: name: observedMutations description: The specific mutations that have been identified and documented in the nucleic acid sequence. title: observed mutations from_schema: https://w3id.org/evorao/ rank: 1000 alias: observedMutations owner: NucleicAcid domain_of: - NucleicAcid range: string required: false multivalued: false identificationTechnique: name: identificationTechnique description: A method or procedure used to detect, identify, and confirm the presence of a specific nucleic acid sequence, pathogen, or associated constructs. This may involve various techniques such as PCR, sequencing, hybridization, or other molecular methods, utilizing specific tools and procedures for accurate detection and analysis. title: identification technique from_schema: https://w3id.org/evorao/ rank: 1000 alias: identificationTechnique owner: NucleicAcid domain_of: - NucleicAcid - Pathogen range: string required: false multivalued: false sequencing: name: sequencing description: Refers to the level of sequencing performed on the nucleic acid. Possible values include 'Not sequenced' (no sequencing has been performed), 'Partly sequenced' (only a portion of the nucleic acid sequence has been determined), and 'Fully sequenced' (the entire nucleic acid sequence has been determined). title: sequencing comments: - Cloned products have to be sequenced. from_schema: https://w3id.org/evorao/ rank: 1000 alias: sequencing owner: NucleicAcid domain_of: - NucleicAcid range: string required: true multivalued: false equals_string_in: - Not sequenced - Partly sequenced - Fully sequenced titer: name: titer description: The titer value, its corresponding unit, and the method of quantification (e.g., RT-qPCR, TCID50), representing the concentration or amount of unit present in the sample. The titer corresponds to the highest dilution factor that still yields a positive reading. title: titer from_schema: https://w3id.org/evorao/ related_mappings: - wd:Q2166189 rank: 1000 alias: titer owner: NucleicAcid domain_of: - NucleicAcid - Pathogen range: string required: false multivalued: false sequenceChecked: name: sequenceChecked description: Tell whether or not the sequence of the product was controlled, which is expected for sequenced nucleic acids and especially important for cloned ones. title: sequence checked comments: - For non-sequenced nucleic acids, the sequenceChecked value cannot be assessed. In all other cases, it is strongly recommended to indicate whether the sequence verification has been performed or not. For cloned products in particular, providing this information is especially meaningful, as sequence verification is a key element in confirming the integrity of the cloned construct and is therefore expected to be documented whenever available. from_schema: https://w3id.org/evorao/ related_mappings: - iceo:0000336 rank: 1000 alias: sequenceChecked owner: NucleicAcid domain_of: - NucleicAcid range: boolean required: false recommended: true multivalued: false iataClassification: name: iataClassification description: The corresponding International Air Transport Association (IATA)'s category for this Product. title: IATA classification from_schema: https://w3id.org/evorao/ close_mappings: - wdp:P238 - schema:iataCode rank: 1000 alias: iataClassification owner: NucleicAcid domain_of: - Product range: IataClassification required: true multivalued: false shippingConditions: name: shippingConditions description: Specification of the terms and parameters for transporting. title: shipping conditions from_schema: https://w3id.org/evorao/ close_mappings: - schema:shippingConditions rank: 1000 alias: shippingConditions owner: NucleicAcid domain_of: - Product range: string required: true multivalued: false materialSafetyDataSheet: name: materialSafetyDataSheet description: A Material Safety Data Sheet (MSDS) or Safety Data Sheet (SDS) is a standardized document that contains crucial occupational safety and health information related to the product. title: material safety data sheet comments: - The MSD is a document that provides detailed information about the properties, hazards, handling, storage, and emergency procedures related to the use of a chemical or substance. from_schema: https://w3id.org/evorao/ rank: 1000 alias: materialSafetyDataSheet owner: NucleicAcid domain_of: - Product range: MaterialSafetyDataSheet required: false multivalued: false originator: name: originator description: The individual or organization responsible for the original discovery, isolation, or creation of an item, providing information about the source or origin of the sample. title: originator from_schema: https://w3id.org/evorao/ close_mappings: - dct:provenance rank: 1000 alias: originator owner: NucleicAcid domain_of: - Product range: Originator required: false multivalued: false storageConditions: name: storageConditions description: Specifies the conditions under which the product has to be stored to maintain stability and integrity, such as temperature, buffer, and other environmental factors. title: storage conditions comments: - e.g, could be a xsd:string in enumeration ('Freeze Dried', 'Liquid Nitrogen', 'Viral Storage Medium -20C', 'Viral Storage Medium -80C', 'Living plant material (>= +4°C)', 'Gas Phase', 'Ethanol -20C', 'Ethanol -80C', 'Dried'). from_schema: https://w3id.org/evorao/ rank: 1000 alias: storageConditions owner: NucleicAcid domain_of: - Product range: string required: true multivalued: false thirdPartyDistributionConsent: name: thirdPartyDistributionConsent description: Indicates whether the biological material can be distributed without restriction to third parties, as indicated by the ABS permit, in case an ABS permit is required. title: third party distribution consent from_schema: https://w3id.org/evorao/ rank: 1000 alias: thirdPartyDistributionConsent owner: NucleicAcid domain_of: - Product range: boolean required: false multivalued: false usageRestrictions: name: usageRestrictions description: Specifies any limitations or conditions on the use of the biological material, including restrictions on research, commercial use, or distribution, considering any potential concerns about the related genetic material. title: usage restrictions from_schema: https://w3id.org/evorao/ rank: 1000 alias: usageRestrictions owner: NucleicAcid domain_of: - Product range: string required: false multivalued: false preparationTechnique: name: preparationTechnique description: The technique, method, or procedure employed to obtain or prepare the material prior to its use or storage. title: preparation technique from_schema: https://w3id.org/evorao/ rank: 1000 alias: preparationTechnique owner: NucleicAcid domain_of: - Product range: string required: false multivalued: false accessPointUrl: name: accessPointUrl description: The URL that permits to access to the product/service detailed description page on the provider's website and/or allows to place an order about it or at least describe the process to place an order/enquiry. title: access point URL from_schema: https://w3id.org/evorao/ exact_mappings: - schema:serviceURL related_mappings: - dcat:landingPage broad_mappings: - schema:url rank: 1000 is_a: iri alias: accessPointUrl owner: NucleicAcid domain_of: - ProductOrService range: uri required: true multivalued: false refSku: name: refSku description: The reference or the stock keeping unit of the service or item provided in the provider's catalogue. title: ref SKU from_schema: https://w3id.org/evorao/ exact_mappings: - schema:sku close_mappings: - dwc:catalogNumber broad_mappings: - dct:identifier - schema:identifier rank: 1000 is_a: identifier alias: refSku owner: NucleicAcid domain_of: - ProductOrService range: string required: true multivalued: false unitDefinition: name: unitDefinition description: A short description of what is delivered when one unit of this item is ordered, such as quantity or packaging. title: unit definition comments: - 'The description of what will be delivered to the end-user (e.g.: packaging, quantity...).' from_schema: https://w3id.org/evorao/ related_mappings: - dct:format rank: 1000 alias: unitDefinition owner: NucleicAcid domain_of: - ProductOrService range: string required: false recommended: true multivalued: false category: name: category description: The main category of the service or product. title: category from_schema: https://w3id.org/evorao/ close_mappings: - schema:category - gr:category rank: 1000 slot_uri: dcat:theme alias: category owner: NucleicAcid domain_of: - ProductOrService range: ProductCategory required: true multivalued: false additionalCategory: name: additionalCategory description: Any category apart from its main category in which this product or service can fit. title: additional category from_schema: https://w3id.org/evorao/ close_mappings: - schema:additionalType rank: 1000 is_a: category alias: additionalCategory owner: NucleicAcid domain_of: - ProductOrService range: ProductCategory required: false recommended: true multivalued: true unitCost: name: unitCost description: The cost per access for one unit as defined by the unit definition. title: unit cost comments: - The cost per access may not always be defined as a fixed numerical value. In some cases, the price is conditional or available only upon request. To accommodate such cases, descriptive information should be provided through the property EVORAO:unitCostNote (xsd:string). This allows handling of cost statements such as “on request,” “depends on volume,” or “free access for academics,” which cannot be captured by a simple numeric value. from_schema: https://w3id.org/evorao/ close_mappings: - schema:price rank: 1000 alias: unitCost owner: NucleicAcid domain_of: - ProductOrService range: decimal required: false recommended: true multivalued: false unitCostCurrency: name: unitCostCurrency description: The currency in which the unit cost is expressed, following ISO 4217 three-letter codes (e.g., EUR, USD). title: unit cost currency from_schema: https://w3id.org/evorao/ close_mappings: - schema:priceCurrency rank: 1000 ifabsent: string(EUR) alias: unitCostCurrency owner: NucleicAcid domain_of: - ProductOrService range: string required: false recommended: true multivalued: false unitCostNote: name: unitCostNote description: A free-text note describing special conditions or cases where the cost cannot be represented by a numerical value (e.g., on request, free for academics, depends on volume). title: unit cost note from_schema: https://w3id.org/evorao/ rank: 1000 alias: unitCostNote owner: NucleicAcid domain_of: - ProductOrService range: string required: false multivalued: false qualityGrading: name: qualityGrading description: Information that permits to assess the quality level of what will be provided. title: quality grading from_schema: https://w3id.org/evorao/ close_mappings: - bao:0002662 - sio:000217 rank: 1000 alias: qualityGrading owner: NucleicAcid domain_of: - ProductOrService range: string required: false multivalued: false pathogenIdentification: name: pathogenIdentification description: The identification of the pathogen or group of pathogens (e.g; name, taxon identification, etc.) related to the current item. title: pathogen identification comments: - 'The pathogen identification contains information about name and taxon but in some cases(e.g: FAIRSHARING) there may have no direct pathogen related but simply a taxonomic information .... the default value should be the root of virology: Viruses.' from_schema: https://w3id.org/evorao/ rank: 1000 alias: pathogenIdentification owner: NucleicAcid domain_of: - ProductOrService range: PathogenIdentification required: true multivalued: true doi: name: doi description: A Digital Object Identifier (DOI) that can be related. title: DOI from_schema: https://w3id.org/evorao/ exact_mappings: - wdp:P356 close_mappings: - wdp:P356 - reproduceme:doi broad_mappings: - dct:bibliographicCitation rank: 1000 alias: doi owner: NucleicAcid domain_of: - ProductOrService - Publication range: Doi required: false multivalued: true riskGroup: name: riskGroup description: The highest risk group related to this resource. The risk group of a biological agent guiding its initial handling in labs according to the risk group classification defined by the WHO laboratory biosafety manual. title: risk group comments: - The Risk Group (RG) assignments to an item are jurisdiction-dependent and may differ between countries/regions and by material form (e.g., live isolate, inactivated preparation, nucleic acid). Assignments can also change over time. We store here a single reference assignment; users must verify the current, locally applicable assignment with their competent authority. from_schema: https://w3id.org/evorao/ exact_mappings: - wdp:P12663 related_mappings: - bao:0002826 rank: 1000 alias: riskGroup owner: NucleicAcid domain_of: - ProductOrService range: RiskGroup required: false recommended: true multivalued: false biosafetyLevel: name: biosafetyLevel description: The level of biocontainment required or applied in the facility where the biological agent is manipulated. title: biosafety level comments: - The Biosafety Level (BSL) reflects the operational safety measures implemented, which may differ from the intrinsic risk defined by the agent’s Risk Group (RG). from_schema: https://w3id.org/evorao/ exact_mappings: - wdp:P1604 - bao:0002826 rank: 1000 alias: biosafetyLevel owner: NucleicAcid domain_of: - ProductOrService range: BiosafetyLevel required: false multivalued: false biosafetyRestrictions: name: biosafetyRestrictions description: Information about guidelines and regulations designed to prevent the exposure to or release of potentially harmful biological agents. It thereby contributes to protecting people and the environment from biohazards while accessing this product or service. title: biosafety restrictions from_schema: https://w3id.org/evorao/ related_mappings: - bao:0002826 - wdp:P12663 - wdp:P1604 rank: 1000 alias: biosafetyRestrictions owner: NucleicAcid domain_of: - ProductOrService range: string required: false multivalued: false canBeUsedToProduceGmo: name: canBeUsedToProduceGmo description: Indicates if the current service or product can be used to produce GMO. title: can be used to produce GMO comments: - Set to TRUE if it can produce GMO. - It is recommended to have a value for this field, no value will be understood as unknown. from_schema: https://w3id.org/evorao/ broad_mappings: - schema:potentialUse rank: 1000 alias: canBeUsedToProduceGmo owner: NucleicAcid domain_of: - ProductOrService range: boolean required: false recommended: true multivalued: false provider: name: provider description: A provider of this product or service, as a specific organization. title: provider from_schema: https://w3id.org/evorao/ exact_mappings: - sio:000066 close_mappings: - schema:provider - dct:publisher rank: 1000 alias: provider owner: NucleicAcid domain_of: - ProductOrService range: Provider required: true multivalued: false collection: name: collection description: The collection(s) to which belongs this item. title: collection from_schema: https://w3id.org/evorao/ related_mappings: - afop:AFX_0002720 broad_mappings: - dct:isPartOf rank: 1000 alias: collection owner: NucleicAcid domain_of: - ProductOrService range: Collection required: true multivalued: true keywords: name: keywords description: List of terms used to tag and categorize this Item. title: keywords from_schema: https://w3id.org/evorao/ exact_mappings: - schema:keywords close_mappings: - dcat:keyword rank: 1000 alias: keywords owner: NucleicAcid domain_of: - ProductOrService range: Keyword required: true multivalued: true availability: name: availability description: The state or condition in which this item is accessible and ready for use or can be obtained. title: availability comments: - Possible availabilities may differ from a project to another. from_schema: https://w3id.org/evorao/ close_mappings: - schema:availability - dct:available rank: 1000 ifabsent: string(on request) alias: availability owner: NucleicAcid domain_of: - ProductOrService range: string required: true multivalued: false complementaryDocument: name: complementaryDocument description: Any additional documents that provide supplementary information, instructions, or guidelines relevant to the use of this item. title: complementary document from_schema: https://w3id.org/evorao/ close_mappings: - sepio:0000442 rank: 1000 alias: complementaryDocument owner: NucleicAcid domain_of: - ProductOrService range: Document required: false multivalued: true technicalRecommendation: name: technicalRecommendation description: Expert advice or guidelines provided to ensure the optimal use, performance, and maintenance of what is provided, including best practices, troubleshooting tips, and procedural instructions. title: technical recommendation from_schema: https://w3id.org/evorao/ rank: 1000 alias: technicalRecommendation owner: NucleicAcid domain_of: - ProductOrService range: string required: false multivalued: false productPicture: name: productPicture description: A picture that can represent the item. title: product picture from_schema: https://w3id.org/evorao/ rank: 1000 alias: productPicture owner: NucleicAcid domain_of: - ProductOrService range: Image required: false multivalued: true externalRelatedReference: name: externalRelatedReference description: A reference that permits to retrieve another related item from an external provider. title: external related reference from_schema: https://w3id.org/evorao/ broad_mappings: - dct:references rank: 1000 alias: externalRelatedReference owner: NucleicAcid domain_of: - ProductOrService range: ExternalRelatedReference required: false multivalued: true certification: name: certification description: Any certification related to the current product or service; e.g., ISO certification. title: certification from_schema: https://w3id.org/evorao/ exact_mappings: - schema:hasCertification close_mappings: - dct:conformsTo rank: 1000 alias: certification owner: NucleicAcid domain_of: - ProductOrService range: Certification required: false multivalued: true internalReference: name: internalReference description: Any reference or indication to be used for local retrieval purpose. title: internal reference from_schema: https://w3id.org/evorao/ broad_mappings: - dct:references rank: 1000 alias: internalReference owner: NucleicAcid domain_of: - ProductOrService range: string required: false multivalued: false note: name: note description: An aditional information as a textual comment. title: note from_schema: https://w3id.org/evorao/ rank: 1000 slot_uri: skos:note alias: note owner: NucleicAcid domain_of: - ProductOrService range: string required: false multivalued: false contactPoint: name: contactPoint description: An information that allows someone to establish communication. title: contact point from_schema: https://w3id.org/evorao/ exact_mappings: - schema:contactPoint rank: 1000 slot_uri: dcat:contactPoint alias: contactPoint owner: NucleicAcid domain_of: - ProductOrService - PersonOrOrganization range: ContactPoint required: false recommended: true multivalued: false fundingSource: name: fundingSource description: A program, grant, or project providing financial support for the access or use of the product or service, either fully or partially. title: funding source comments: - Links a product or service to one or more financial mechanisms, initiatives, or grants that enable or support its provision or access. from_schema: https://w3id.org/evorao/ exact_mappings: - schema:funding rank: 1000 alias: fundingSource owner: NucleicAcid domain_of: - ProductOrService range: FundingSource required: false multivalued: true title: name: title description: A name given to the resource. title: title comments: - The title of the item should be as short and descriptive as possible. - 'E.g. for virus products it should basically be based on the following Pattern: ''Virus name'', ''virus host type'', ''collection year'', ''country of collection'' ex ''suspected epidemiological origin'', ''genotype'', ''strain'', ''variant name or specific feature.' from_schema: https://w3id.org/evorao/ exact_mappings: - schema:name - rdfs:label rank: 1000 slot_uri: dct:title alias: title owner: NucleicAcid domain_of: - Dataset - DataService - Publication - Term - License - Certification - FundingSource range: string required: true multivalued: false description: name: description description: A short explanation of the characteristics, features, or nature of the current item. title: description comments: - Describe this item in few lines. This description will serve as a summary to present the resource. from_schema: https://w3id.org/evorao/ exact_mappings: - schema:description rank: 1000 slot_uri: dct:description alias: description owner: NucleicAcid domain_of: - Dataset - DataService - Term - PersonOrOrganization - File - ContactPoint - License - Certification - FundingSource range: string required: true recommended: true multivalued: false version: name: version description: The version indicator (name or identifier) of a resource. title: version from_schema: https://w3id.org/evorao/ exact_mappings: - pav:version close_mappings: - wdp:P393 - schema:version related_mappings: - schema:identifier rank: 1000 slot_uri: dcat:version alias: version owner: NucleicAcid domain_of: - Dataset - Version - Taxonomy range: string required: false recommended: true multivalued: false keyword: name: keyword description: A keyword or tag describing the resource. title: keyword from_schema: https://w3id.org/evorao/ rank: 1000 slot_uri: dcat:keyword alias: keyword owner: NucleicAcid domain_of: - Resource range: string required: false multivalued: true dateIssued: name: dateIssued description: Date of formal issuance (e.g., publication) of the resource. title: date issued comments: - encoded using the relevant ISO 8601 Date and Time compliant string [DATETIME]. from_schema: https://w3id.org/evorao/ exact_mappings: - sepio:0000051 close_mappings: - schema:datePublished - schema:dateCreated rank: 1000 slot_uri: dct:issued alias: dateIssued owner: NucleicAcid domain_of: - Resource range: datetime required: false multivalued: false dateModified: name: dateModified description: Most recent date on which the resource was changed, updated or modified. title: date modified comments: - encoded using the relevant ISO 8601 Date and Time compliant string [DATETIME]. from_schema: https://w3id.org/evorao/ exact_mappings: - sepio:0000036 close_mappings: - schema:dateModified rank: 1000 slot_uri: dct:modified alias: dateModified owner: NucleicAcid domain_of: - Resource range: datetime required: false multivalued: false identifier: name: identifier description: A unique identifier of the resource being described or cataloged. title: identifier comments: - The identifier is a text string which is assigned to the resource to provide an unambiguous reference within a particular context. Persistent identifiers should be provided as HTTP URIs. from_schema: https://w3id.org/evorao/ exact_mappings: - schema:identifier rank: 1000 slot_uri: dct:identifier alias: identifier owner: NucleicAcid domain_of: - Resource range: string required: false multivalued: true iri: name: iri description: International Resource Identifier (IRI) that uniquely identifies or refers to the resource. IRIs include URIs, and URIs include URLs. title: IRI comments: - An IRI is a global identifier standardized by IETF RFC 3987. It may or may not be resolvable on the web. IRIs include URIs, and URIs include URLs. from_schema: https://w3id.org/evorao/ close_mappings: - biolink:iri related_mappings: - mi:url narrow_mappings: - schema:url rank: 1000 is_a: identifier alias: iri owner: NucleicAcid domain_of: - Resource range: uri required: false multivalued: true publisher: name: publisher description: The entity responsible for making the resource available. title: publisher comments: - Resources of type foaf:Agent like EVORAO:PersonOrOrganization are recommended as values for this property. from_schema: https://w3id.org/evorao/ rank: 1000 slot_uri: dct:publisher alias: publisher owner: NucleicAcid domain_of: - Resource range: PersonOrOrganization required: false multivalued: false ```